SENNA (CASSIA ANGUSTIFOLIA)

Senna is an FDA (Food and Drug Administration) approved nonprescription laxative herb. It is used to treat constipation and also to clear the bowel before diagnostic tests such as colonoscopy. Senna is also used for irritable bowel syndrome (IBS), hemorrhoids and weight loss.

 

Senna contains many chemicals called sennosides. Sennosides irritate the lining of the bowel, which causes a laxative effect. (Ph.Eur. p-1652)

 

Senna is an anthranoid-type stimulating laxative. The laxative effect is due to the action of sennosides and their active metabolite, rhein anthrone, in the colon. The laxative effect is realized by inhibition of water and electrolyte absorption from the large intestine, which increases the volume and pressure of the intestinal contents. This will stimulate colon motility resulting in propulsive contractions. (pdr. P-935) This has led the American Herbal Products Association (AHPA) to warn against long-term use of senna leaf, but not senna fruit. 

 

Do not use this product if you have abdominal pain or diarrhea. Consult a healthcare provider prior to use if you are pregnant or nursing. And discontinue use in the event of diarrhea or watery stools. Do not exceed recommended dose. It is not for long-term use.

 

References:

1. European Pharmacopoeia Tenth Edition, Volume I, P-1652

2. PDR for Herbal Medicines, 4th edition, Updated Botanical Monographs p-935.